Retatrutide read out 5 Phase 3 trials, with 45.3% of people on the top dose losing over 30% of their weight. The post lists several recent peptide approvals and policy changes.
Key points
First drugmaker to reach a $1 trillion valuation did so on a peptide.
First oral peptide for psoriasis approved; 65% had clear or almost clear skin at 16 weeks vs 8% on placebo.
Daily peptide pill approved that lowers LDL cholesterol by more than half.
Sources
Checkpoint immunotherapy reorganized cells in melanoma
Checkpoint immunotherapy reorganized immune cells in melanoma-involved lymph nodes in a preclinical model, showing greater separation between macrophages and T cells. The result was observed in a preclinical study.
Key points
Reorganized immune cells in melanoma-involved lymph nodes in a preclinical model
Greater separation between macrophages and T cells
Sources
- Original post
- medicalxpress.com - Linked in the post
GLiFormer large missed disease mentions, fine-tune found them
GLiFormer large missed five disease mentions in a synthetic note. A fine-tune recovered them, increasing detections from 18 to 25 on the same note with the same threshold.
Key points
Missed mentions: dyspnea, orthopnea, leg swelling, pulmonary edema, pleural effusion.
Fine-tune result: 25 disease mentions detected versus 18 originally.
Sources
Payments $45 influence anticancer drug prescribing
Payments as small as $45 are linked to prescribing decisions for anticancer drugs that can cost tens of thousands of dollars per month. The claim appears in a guest post discussing a recent editorial.
Key points
Payments: $45 amount associated with prescribing decisions.
Drug cost: tens of thousands of dollars per month.
Sources
- Original post
- theoncologyshot.com - Linked in the post
Kin launches Apple Watch recording feature for visit summaries
Kin adds Apple Watch support, letting users tap Record on the wrist to capture visits and receive plain-English summaries on their iPhone. The watch records phone calls when placed on speaker and delivers next-step instructions to the phone.
Key points
Feature: Tap Record on your wrist, phone stays in pocket.
Feature: Phone visit? Put it on speaker and your watch records it.
