LiteFold reports that recovery during Protein A purification fell from 92% to 75% across three consecutive batches in its Dupilumab manufacturing example. The drop was observed batch-by-batch, indicating a gradual loss of efficiency.
Key points
Recovery rate: 92% initially, then 75% after three batches.
Process: Protein A purification step in Dupilumab production.
Sources
Claude Fable 5.2 creates three devices from brief prompt
Claude Fable 5.2 designed three working electronic devices from a one-paragraph prompt. One of the devices is a home voice assistant hub.
Key points
Designed three working electronic devices from a one-paragraph prompt.
Included a home voice assistant hub among the devices.
Sources
ClaudeAI Mythos 5.2 launch shows big jump
ClaudeAI Mythos 5.2 is released and produces a big jump in performance on TahoeMysts. The team defines verifiable biological reasoning tasks using ground-truth experimental data and has built thousands of TahoeMyst environments for evaluation.
Key points
TahoeMysts are thousands of environments created to evaluate frontier models.
Verifiable rewards require answer keys from ground-truth experimental data.
Sources
soil bacterium linked to infections in Mississippi
soil bacterium linked to multiple infections in Mississippi, suggesting a foothold in the continental US beyond its long-known tropical range. The post highlights new US cases of this potentially deadly bacterium.
Key points
Linked to multiple infections in Mississippi
Suggests foothold in continental US beyond long-known tropical range
Sources
- Original post
- medicalxpress.com - Linked in the post
Synthetic circuit shrank tumors in mice, no toxicity
Synthetic circuit shrank tumors in mice by converting protein-making errors into a kill switch. No inflammation or organ toxicity was detected in healthy major organs.
Key points
Tumor shrinkage achieved in mice using a synthetic circuit.
No inflammation or organ toxicity observed in healthy tissues of major organs.
Sources
- Original post
- medicalxpress.com - Linked in the post
PierreFabre collaboration de novo small-molecule design with robotic feedback
PierreFabre collaboration announces de novo small-molecule design tightly coupled with robotic lab feedback for oncology programs. The approach focuses on tighter design-to-experiment loops rather than larger models.
Key points
Collaboration with PierreFabre for de novo small-molecule design.
Robotic lab feedback integrated in multiple oncology programs.
Sources
Chemify launches new website and chemifarms initiative
Chemify unveiled a new website and announced worldwide chemifarms for chemputation. The platform demonstrated production scales from 1 mg to over 40 g.
Key points
New website unveiled.
Demonstrated scale from 1 mg to over 40 g on one platform.
Sources
- Original post
- Chemify - Linked page