10-protein blood panel distinguishes ALS patients from healthy people with nearly 98% balanced accuracy. It outperforms a leading biomarker, but testing against similar conditions is still needed.
Key points
10-protein blood panel achieved nearly 98% balanced accuracy distinguishing ALS patients from healthy people
Outperformed a leading biomarker; further testing against similar conditions required
Sources
- Original post
- medicalxpress.com - Linked in the post
OpenMed 3.1 split_overlap prevents scoring held-out pairs
OpenMed 3.1 cannot score a split where 3 of the 12 held-out pairs in a clinical NLI evaluation also appear in the dev set. The split is labeled split_overlap, the model is never loaded, and any change to the weights after sign-off causes the run to be refused.
Key points
3 of the 12 held-out pairs also sit in the dev set.
OpenMed 3.1 won’t score split_overlap and the model is never loaded.
Sources
SWE-rebench V2.1 RL release – 13,337 free RL environments
SWE-rebench V2.1 RL is out with 13,337 free RL environments for coding agents in 20 languages using Harbor format. Fixed tasks, envs, and graders provide fast, reliable rollouts.
Key points
13,337 free RL environments for coding agents (20 languages, Harbor format)
Fixed tasks, envs, and graders enable fast, reliable rollouts
Sources
Ez-PAVE statin-ezetimibe combo similar efficacy and safety
Ez-PAVE using a treat-to-target LDL-C strategy found that starting with statin-ezetimibe combination therapy or statin monotherapy gave similar cardiovascular efficacy and safety. The finding was presented at Scientific Sessions 26.
Key points
Combination therapy vs monotherapy gave similar cardiovascular efficacy.
Combination therapy vs monotherapy gave similar safety.
Sources
- Original post
- ahajrnls.org - Linked in the post
Immune cells - drive placental inflammation in preterm
Immune cells drive placental inflammation in preterm cases, while full-term cases have more healing and anti-inflammatory cells. Reported by @wustl and @sciencetm.
Key points
Finding: immune cells from both mother and baby drove aggressive placental inflammation in preterm cases
Finding: full-term cases had more cells that support healing and control inflammation
Sources
- Original post
- medicalxpress.com - Linked in the post
Function panel at Eudemonia Summit – 8 of 10 members act on results
Function’s Women’s Health Medical Director Tiffany Lester discussed turning results into action at the Eudēmonia Summit. 8 out of 10 Function members take action based on their results. The booth is #601 in the Expo.
Key points
8 out of 10 Function members take action based on what they learn from their results.
Booth #601 in the Expo; find it by taking a right at the entrance and looking for plants.
Sources
WrightState tenfold reduction restores vessel function
WrightState reports a tenfold reduction in tiny cell-released particles restored normal blood vessel function in lab tests with severe early-onset preeclampsia samples. The result is not yet a treatment.
Key points
Tenfold reduction in tiny cell-released particles
Restored normal blood vessel function in lab tests using severe early-onset preeclampsia samples
Sources
- Original post
- Linked resource - Linked in the post
From model to medicine: cardiovascular AI event
From model to medicine: the future of cardiovascular AI will be discussed at a Scientific Sessions event on Nov. 8. The session runs 8-9:15 AM CT in room N228 and includes AI investigators and journal leaders such as @CircAHA.
Key points
AI investigators & leaders of major journals, including @CircAHA, will discuss the modern evidence lifecycle of AI from development through deployment.
Nov. 8 | 8-9: 15 AM CT | N228, part of #ScientificSessions26.
