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XtalPi hair-loss candidate enters enabling studies

, 4 items in AI in Healthcare and Science, 2 min read

In this digest (4 items)

XtalPi announced its hair-loss candidate is in enabling studies. The candidate works at 1/100th the concentration and shows comparable hair-growth scores to 5% minoxidil in a mouse model. It targets dormant follicle stem cells through a different biological pathway.

Key points

  • Concentration: 1/100th the concentration.

  • Performance: Comparable hair-growth scores to 5% minoxidil in a mouse model.

Sources

AI Lift cohort for researchers announced

AI Lift is a program for researchers. The first cohort includes work on cancer drug discovery and computer vision. Support comes from @Nebius_Academy and Nebius Science.

Key points

  • Cohort: first cohort of AI Lift for researchers

  • Support: @Nebius_Academy and Nebius Science​

Sources

Intensive breathing cuts brain blood flow up to 45%

Intensive breathing exercises reduce cerebral blood flow by up to 45%. Stronger altered states were linked to greater changes in the brain's default mode network, which supports self‑reflection.

Key points

  • Global gray‑matter cerebral blood flow fell by around 45% during the session, on average from 16.24 to 9.81 ml/100g/min.

  • Those who reported stronger altered states also showed greater changes in the brain's default mode network, which is involved in self‑reflection.

Sources

Anodal M1 tDCS reduces thermal pain in triple‑blind trial

Anodal M1 transcranial direct current stimulation (tDCS) reduced thermal pain compared with sham in a pre‑registered, triple‑blind trial of 50 participants. Cathodal stimulation increased pain compared with sham. The polarity‑dependent effects were stable across 35 minutes post‑stimulation.

Key points

  • Anodal M1 #tDCS effect size: Cohen's d = 0.85 versus sham.

  • Cathodal stimulation effect size: Cohen's d = 0.34 versus sham; effects stable for 35 min.

Sources