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Retatrutide hit ~28% weight loss in a phase 3

, 5 items in AI Holodeck and Virtual Worlds, 3 min read

In this digest (5 items)

Retatrutide achieved roughly 28% weight loss in a phase 3 trial. The post lists recent biotech results with specific efficacy numbers and timelines.

Key points

  • Once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months).

  • One-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months.

  • Personalized mRNA vaccine beat Keytruda alone in a 1,137-patient melanoma phase 3.

  • AI-designed drug entered phase 3.

Sources

Idol – open image-to-3D model with 600M params

Idol is an open image-to-3D model that generates full 3D objects from a single image, using 600M parameters and under 7.2GB VRAM. It can produce 1M Gaussian splats in about 3 seconds on consumer GPUs.

Key points

  • Parameters: 600M

  • Speed: 1M splats in 3 s

Sources

VEED Dubbing now in ComfyUI, Pro adds precise lip-sync

VEED Dubbing is now available in ComfyUI. It translates speech into another language, clones each speaker’s voice, and lip-syncs while keeping tone and emotion. The Pro version adds precise lip-sync, keeps the original background audio and handles multi-speaker videos.

Key points

  • Translates speech into another language

  • Clones each speaker’s voice

Sources

Storylines live on Civitai, start collaborative stories

Storylines is live on Civitai, letting anyone start a story and write the next chapter. Each chapter is a post and the story branches from any chapter.

Key points

  • Launch: Storylines is live on Civitai.

  • Feature: Each chapter is a post and stories branch from any chapter.

Sources

Kimodo motion layer adds dedicated animation toolset

Kimodo motion layer adds a dedicated animation toolset that runs in the browser via ThreeJS. It lets agents run the same workflow autonomously and supports multiple image pose constraints with additive control rig editing.

Key points

  • Hosted MCP now lets your agent accomplish this same workflow on its own.

  • Multiple images can be used as pose constraints to guide Kimodo generations, fully editable afterwards via additive control rig.

Sources